Wells LabUCSF, Depts of Pharmaceutical Chemistry and Cellular and Molecular Pharmacology
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Lab Members

Principal Investigator

Jim Wells, Ph.D.
Professor

University of California San Francisco
Department of Pharmaceutical Chemistry
Phone: 1-415-514-4498
Email: Jim.Wells at ucsf.edu
www.epernicus.com/jaw2

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Coordinators

Rong Mao, Ph.D.
Academic Coordinator III
Project: Fund-raising
Phone: 1-415-514-4504
Email: rong.mao at ucsf.edu

Marja Tarr
Administration
Phone: 1-415-514-4757
Email: Marja.Tarr at ucsf.edu

Allison Doak
Lab manager
B.S. University of Wisconsin - Madison
Email: allison.doak at ucsf.edu

PostDocs

Juan Diaz, Ph.D.
Ph.D. University of California, Irvine
B.S. California State University, Fullerton
Project: Split Constructs
Email: Juan.Diaz at ucsf.edu

Zachary Hill, Ph.D.
Ph.D. University of Washington
B.S. University of Alaska Fairbanks
Project: Target Validation of Small-Molecule Inhibitors
Email: Zachary.Hill at ucsf.edu

Olivier Julien, Ph.D.
Ph.D. University of Alberta
B.S. Université Laval
Project: Caspases in differentiation
Email: Olivier.Julien at ucsf.edu

Paul Marinec, Ph.D.
Ph.D. University of Michigan
B.S. University of Michigan
Project: Antibody Engineering Extraordinare
Email: Paul.Marinec at ucsf.edu

Duy Nguyen, Ph.D.
Ph.D. University of Cambridge, U.K.
B.A. Franklin and Marshall College
Project: CRISPR engineering
Email: Duy.Nguyen at ucsf.edu

Amy Weeks, Ph.D.
Ph.D. University of California, Berkeley
B.S. Massachusetts of Institute of Technology
Project: Subtiligase engineering
Email: weeksam at gmail.com

Graduate Students

Alex Martinko
B.A. University of Colorado, Boulder
Project: Oncogene Induced Modulation of the Extracellular Proteome
Email: Alexander.Martinko at ucsf.edu

Charles Morgan
B.A. Lewis and Clark College
Project: Apoptotic Nodes
Email: Charles.Morgan at ucsf.edu

Sam Pollock
B.A. University of Chicago
Project: NEDDylator
Email: sam.pollock at ucsf.edu

Justin Rettenmaier
B.S. University of California, Santa Cruz
Project: Small Molecule Activators of Kinases
Email: Terry.Rettenmaier at ucsf.edu

Julia Seaman
B.A. Pomona College
Project: Apoptosis and biomarkers in mice
Email: Julia.Seaman at ucsf.edu

Ashley Smart
B.A. Pomona College
Project: Apoptotic Nodes
Email: Ashley.Smart at ucsf.edu

Hai Tran
B.S. Emory University
Project: Natural Products
Email: htran at ucsf.edu

Lab Specialists

Michael Hornsby, Ph.D.
Ph.D. University of California, Davis
B.S. Oregon State University
Project: Proteome-Antibody Center
Email: michael.hornsby at ucsf.edu

Brian Lee, Ph.D.
Ph.D. Massachusetts Institute of Technology
B.S. University of Chicago
Project: Proteome-Antibody Center
Email: brianlee at recombinant-antibodies.org

Tet Matsuguchi, Ph.D.
Ph.D. University of California, San Francisco
B.S. Massachusetts Institute of Technology
Project: Proteome-Antibody Center
Email: tetsuya.matsuguchi at ucsf.edu

Karolina Wypisniak
M.Sc. Humboldt University of Berlin
B.S. University Hamburg
Project: Proteome-Antibody Center
Email: Karolina.Wypisniak at recombinant-antibodies.org

Lab Technicians

Maria Diaz
Lab Technician
Email: maria-elena.diaz at ucsf.edu

Ula Soegianto
Lab Technician
Email: ulasoegianto at yahoo.com

ALUMNI

Nick Agard, Ph.D.
Former Postdoctoral Fellow
Project: Substrates of inflammatory caspases and cellular enzymology
Current position: Scientist at Codexis

Mary Betlach, Ph.D.
Former Academic Coordinator III
Project: Fund-raising
Current position: enjoy your retirement Mary!

Chan Hee Choi
B.S. University of Chicago
Project: Proteome-Antibody Center

Emily Crawford, Ph.D.
Former Graduate Student
Ph.D. University of California, San Francisco
A.B. Bryn Mawr College
Project: Evolution of caspases and their substrates
Current position: Postdoc, University of California, San Francisco

Deb Datta, Ph.D.
Former Graduate Student
Project: Allosteric circuitry and natural regulators of caspase-1
Current position: UCSF Medical School

Junjun Gao, Ph.D.
Former Postdoctoral Fellow
Project: Conformationally selective antibodies
Current position: Viral biochemistry group, Roche Palo Alto

Dan Gray, Ph.D.
Former Graduate Student
Project: Chemically-inducible proteases.
Current position: Scientist at Warp Drive Bio

Gerald Hsu, M.D. Ph.D.
Former Postdoctoral Fellow
Project: Apoptotic biomarkers
Current position: Harvard Medical School

Sean Hudson, Ph.D.
Ph.D. University of Cambridge, UK
B.S. University of Adelaide, Australia

JT Koerber, Ph.D.
Former Postdoctoral Fellow
Ph.D. University of California, Berkeley
B.S. University of Illinois
Current position: Scientist at Genentech

Sami Mahrus, Ph.D.
Former Postdoctoral Fellow
Project: Global Profiling of Proteolysis in Apoptosis
Current position: Scientist at Genentech

Chris McClendon, Ph.D.
Former Graduate Student
Project: Computational modeling of allostery
Current position: Postdoc, University of California, San Diego

Huy Nguyen, M.D.
Former Fellow, Hematology/Oncology
Project: Identification of apoptotic peptide signatures for use as diagnostic biomarkers in hematologic malignancies.
Current position: Kaiser Permanente Moanalua Medical Center, Hawaii

Enrique Perez-Paya, Ph.D.
Former Postdoctoral Fellow
Project: Caspase enzymology
Current location: Cipf – Csic, Valencia, Spain

Alexei Polishchuk, M.D. Ph.D.
M.D./Ph.D. University of Pennsylvania
A.B. Princeton University
Project: Radiation and tyrosine kinase inhibitor-induced cell death in lung cancer

Jason Porter, Ph.D.
Former Postdoctoral Fellow
Ph.D. University of Arizona
B.S. Millersville University of Pennsylvania
Project: Split Constructs
Current position: AAAS S&T Policy Fellow, US Agency for International Development, Washington DC

Yingfeng Qiao, Ph.D.
Former Postdoctoral Fellow
Project: Tethering of RAS
Current position: UCSF School of Pharmacy

Jack Sadowsky, Ph.D.
Former Postdoctoral Fellow
Project: Allosteric modulation of protein kinases.
Current position: Scientist at Genentech

Nathan Thomsen, Ph.D.
Former Postdoctoral Fellow
Ph.D. University of California, Berkeley
B.S. Whitman College
Current position: Scientist at Gilead

Kazutaka Shimbo, Ph.D.
Former Postdoctoral Fellow
Ph.D. University of Tokyo
B.S. Hokkaido University
Project: Apoptotic markers in cancer cells
Current position: Ajinomoto, Japan

Hikari Yoshihara, Ph.D.
Former Postdoctoral Fellow
Project: Kinase tethering and tags for N-terminomics
Current position: Centre Hospitalier Universitaire Vaudois (CHUV), Switzerland

Pete Wildes , Ph.D.
Former Postdoctoral Fellow
Project: Extracellular protease signaling
Current position: Senior Scientist / Project Leader at DuPont Industrial Biosciences

Arun Wiita, M.D. Ph.D.
M.D./Ph.D. Columbia University
B.S. Princeton University
Project: Human apoptotic biomarkers
Current Position: Assitant Professor, UCSF

Dennis Wolan, Ph.D.
Former Postdoctoral Fellow
Project: Structure and regulation of caspases by small molecules
Current position: Assitant Professor, The Scripps Research Institute, San Diego

Julie Zorn, Ph.D.
Former Graduate Student
Ph.D. University of California, San Francisco
B.S. New York University
Project: Small Molecule Activators of Procaspases
Current position: Postdoc, University of California, Berkeley

Min Zhuang, Ph.D.
Former Postdoctoral Fellow
Ph.D. University of Tennessee / St. Jude Children's Research Hospital
B.S. Nanjing University
Project: NEDDylator
Current position: Assitant Professor, ShanghaiTech University